ANAPLASTIC CARCINOMA PDF Print E-mail
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Friday, 11 December 2009 08:56
ANAPLASTIC CARCINOMA
Age: Elderly people
Growth:Very rapid growth to infiltrate thyroid and surroundings.
Pathology:
ÄMAC: Hard nodular mass
ÄMIC: Two types:
Small cell type ® mistaken for lymphosarcoma.
Giant cell type ® mistaken for fibrosarcoma.
Ä Spread: Early by blood and lymphatics.

Treatment:
Ä Surgery: difficult (only justifiable if there is no extracapsular infiltration and evidence of metastases). Decompression isthmectomy is better than tracheostomy which is best avoided.
Ä Radiotherapy: is the best line as it is radiosensitive. Also Adriamycine may be helpful as a palliative chemotherapy.
Prognosis: very bad.
SOURCE: Prof. AYMAN SALEM'S BOOK
Copyright: (Vascular Society of Egypt ) & (Medical Educational web)
Not to be reproduced without permission of Vascular Society of Egypt
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