NAEVI (MOLES) (Definition - Pathology - Clinical Picture

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NAEVI (MOLES) (Definition - Pathology - Clinical Picture - Treatment )

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Thursday, 10 December 2009 20:49

Usually occurs at birth as "birth marks" and less often appears in childhood or adult life  cellular naevi.
Histologically: Moles are divided into:
1- Simple (Intradermal) naevus:
 Pigment cells are found in the dermis.
 It is usually hairy with no tendency to malignant change.
2- Junctional naevus:
 Pigment cells occurs in basal cell layer of epidermis extending into the dermis.
 It is usually hairless (In the palm or foot).
 Malignant change is liable to occur.
3- Compound naevus:
 Masses of pigment cells in the dermis with separate junctional activity.
 Rarely change malignant.
4- Two Special types:
A- Blue naevus: The pigmented cells are spindle shaped. It affect face, hand & buttocks. It is liable to change malignant.
B- Freckles*Simulate junctional naevus in histology.
*It affects exposed parts of blond and red haired people.
*Hutchinson 's freckle (Lentigo maligna) is one type of freckles of special importance as it is considered a precancerous melanotic lesion affecting the face of elderly people.
Treatment: Excision is indicated in:
(1) Dangerous area "Liable to turn malignant".
 Sole, palm, nail bed and cheek of male "due to frequent irritation in shaving".
(2) Criteria of turning malignant:  See later.
SOURCE: Prof. AYMAN SALEM'S BOOK
Copyright: (Vascular Society of Egypt ) & (Medical Educational web)
Not to be reproduced without permission of Vascular Society of Egypt

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